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Western Journal of Nursing Research, Vol. 22, No. 4, 460-474 (2000)
DOI: 10.1177/01939450022044520

Cost-Effectiveness Analysis Methods for the REACT Study

Vanessa Duren-Winfield

Department of Public Health Sciences, Section on Social Sciences and Health Policy, Wake Forest University School of Medicine

Michael J. Berry

Department of Health and Exercise Science, Wake Forest University

Sue A. Jones

Department of Public Health Sciences, Section on Social Sciences and Health Policy, Wake Forest University School of Medicine

Doris H. Clark

Department of Public Health Sciences, Section on Social Sciences and Health Policy, Wake Forest University School of Medicine

Mary Ann Sevick

Department of Public Health Sciences, Section on Social Sciences and Health Policy, Wake Forest University School of Medicine

The Reconditioning Exercise and Chronic Obstructive Pulmonary Disease Trial (REACT) is a two-arm randomized clinical trial designed to compare short-term versus long-term exercise intervention in terms of physical function, acute exacerbation of chronic obstructive pulmonary disease, health-related quality of life, and cost-effectiveness. Clinical trials such as REACT are now routinely paired with economic analyses, and nurses can expect to play a growing role in the conduct of these studies. This article describes a model that is useful for structuring economic evaluations of health care interventions, and illustrates a cost-effectiveness analysis that is being conducted in conjunction with the REACT study. An in-depth description of collection methods and procedures is provided, as well as a summary of recruitment and retention experience to date.


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